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Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex

✍ Scribed by Lin Xu; Ling-Hui Zeng; Michael Wong


Book ID
113812314
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
540 KB
Volume
34
Category
Article
ISSN
0969-9961

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## Abstract Tuberous sclerosis complex (TSC) is a familial tumor syndrome characterized by the development of hamartomas in the brain, heart, kidney, and skin. Disease‐causing mutations in the __TSC1__ or __TSC2__ gene result in constitutive activation of the highly conserved mTOR signal transducti