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BCL3 rearrangement, amplification and expression in diffuse large B-cell lymphoma

โœ Scribed by Hazem A.H. Ibrahim; Furrat Amen; Alistair G. Reid; Kikkeri N. Naresh

Book ID
114795406
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
222 KB
Volume
87
Category
Article
ISSN
0902-4441

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โœ Schuetz, J M; Johnson, N A; Morin, R D; Scott, D W; Tan, K; Ben-Nierah, S; Boyle ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 400 KB

BCL2 is deregulated in diffuse large B-cell lymphoma (DLBCL) by the t(14;18) translocation, gene amplification and/or nuclear factor-kB signaling. RNA-seq data have recently shown that BCL2 is the most highly mutated gene in germinal center B-cell (GCB) DLBCL. We have sequenced BCL2 in 298 primary D