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Bayesian analysis of phase I clinical trials

โœ Scribed by Joel B. Greenhouse; Constantine A. Gatsonis


Book ID
113297036
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
62 KB
Volume
11
Category
Article
ISSN
0197-2456

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โœ Daniel F. Heitjan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 111 KB ๐Ÿ‘ 2 views

Many popular sequential phase II clinical trial designs optimize some criterion subject to constraints on the error probabilities at null and alternative values of the response rate. Such designs may forfeit optimality if one fails to conduct analyses strictly according to plan. Moreover, a decision