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Basic hydrolysis of glyceryl nitrate esters. II. 1,2-glyceryl and 1, 3-glyceryl dinitrate esters

✍ Scribed by C. Capellos; W. J. Fisco; C. Ribaudo; V. D. Hogan; J. Campisi; F. X. Murphy; T. C. Castorina; D. H. Rosenblatt

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
718 KB
Volume
16
Category
Article
ISSN
0538-8066

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✦ Synopsis

Kinetics of the basic hydrolysis of l,2-glyceryl dinitrate (1,2-DNG) and 1,3-glyceryl dinitrate (1,3-DNG) esters were investigated in C0,-free aqueous calcium hydroxide solutions. The hydrolysis reactions were carried out in a temperature controlled reactor vessel with provision for continuous N, sparging of the reaction mixture. Both glyceryl dinitrate esters hydrolyzed via second-order reaction at 25°C. 1,2-DNG in basic solutions isomerized to 1,3-DNG which subsequently hydrolyzed to yield products. The main hydrolysis product of 1,3-DNG was identified as glycidyl nitrate. Other products formed during the basic hydrolysis of DNGs were nitrites and nitrates.

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