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Basic Fibroblast Growth Factor Binds to Heparan-Sulfate in the Extracellular Matrix of Rat Growth Plate Chondrocytes

✍ Scribed by S.K. Chintala; R.R. Miller; C.A. Mcdevitt


Book ID
115564923
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
634 KB
Volume
310
Category
Article
ISSN
0003-9861

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Confluent cultures of human endothelial cells deposit into extracellular matrix (ECM) distinct heparan sulfate proteoglycans (HSPG) which modulate acidic fibroblast growth factor's (aFGF) ability to stimulate human endothelial cell mitogenic capacity. Extracellular matrix 'IS-HSPG were isolated from