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Balanced Synthesis of Light and Heavy Chains of Immunoglobulin G

✍ Scribed by ASKONAS, BRIGITTE A.; WILLIAMSON, ALAN R.


Book ID
109660255
Publisher
Nature Publishing Group
Year
1967
Tongue
English
Weight
507 KB
Volume
216
Category
Article
ISSN
0028-0836

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Co-translational modification of nascent
✍ Bergman, Lawrence W. ;Kuehl, W. Michael πŸ“‚ Article πŸ“… 1979 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 1002 KB

## Abstract We have investigated the in vivo co‐translational covalent modification of nascent immunoglobulin heavy and light chains. Nascent polypeptides were separated from completed polypeptides by ion‐exchange chromatography of solubilized ribosomes on QAE‐Sephadex. First, we have demonstrated