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Regulatory Genes controlling the Synthesis of Heavy Chains of Human Immunoglobulin-G

✍ Scribed by LOBB, NOELENE; CURTAIN, C. C.; KIDSON, CHEV


Book ID
109656988
Publisher
Nature Publishing Group
Year
1967
Tongue
English
Weight
354 KB
Volume
214
Category
Article
ISSN
0028-0836

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## Abstract Although human IgG heavy chain genes encode a C‐terminal lysine, this residue is mostly absent from the endogenous antibodies isolated from serum. Some low but variable level of C‐terminal lysine is present on therapeutic antibodies expressed in mammalian cell culture systems. Here, we