The presence of free light chains (FLC) was investigated in 32 patients with clinically definite or laboratory supported definite multiple sclerosis (MS), 2 patients with neurosyphilis and 10 normal controls. The detection of FLC in unconcentrated cerebrospinal fluid (CSF) was performed by means of
Intrathecal synthesis of free immunoglobulin light chains in multiple sclerosis
β Scribed by M. Krakauer; H. Schaldemose Nielsen; J. Jensen; F. Sellebjerg
- Book ID
- 109336832
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 481 KB
- Volume
- 98
- Category
- Article
- ISSN
- 0001-6314
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Cerebrospinal fluid (CSF) and serum samples from patients with multiple sclerosis and other neurological diseases were examined by capillary isotachophoresis (ITP). The percentage and the rate of synthesis of CSF IgG which migrated slowly with ITP were calculated. CSF specimens of most patients with
The presence of measles antibodies in serum immunoglobulin G fractions from seven patients affected with multiple sclerosis was investigated with HI technic. The kappa-lambda light chain ratios of all samples under investigation were evaluated. Three multiple sclerosis patients, who displayed either