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BAK1 gene variation and abdominal aortic aneurysms

✍ Scribed by Bruce Gottlieb; Lorraine E. Chalifour; Benjamin Mitmaker; Nathan Sheiner; Daniel Obrand; Cherrie Abraham; Melissa Meilleur; Tomoko Sugahara; Ghassan Bkaily; Morris Schweitzer


Book ID
102265714
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
77 KB
Volume
30
Category
Article
ISSN
1059-7794

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BAK1 gene variation and abdominal aortic
✍ Bruce Gottlieb; Lorraine E. Chalifour; Benjamin Mitmaker; Nathan Sheiner; Daniel 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

We sought to examine the role of genetics in the multifactorial disease, abdominal aortic aneurysm (AAA), by studying sequence variation in the BAK1 gene (BAK1) that codes for an apoptotic-promoting protein, as chronic apoptosis activation has been linked to AAA development and progression. BAK1 abd

A response to: BAK1 gene variation and a
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We thank Ku ¨ry et al. [2010] for their letter. They raise a number of issues with regard to our initial article that reported on variations in BAK1 gene (MIM] 600516) sequence expressed in the abdominal aorta (AA) tissue when compared with leukocyte genomic DNA sequence . In a subsequent letter , w

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