We sought to examine the role of genetics in the multifactorial disease, abdominal aortic aneurysm (AAA), by studying sequence variation in the BAK1 gene (BAK1) that codes for an apoptotic-promoting protein, as chronic apoptosis activation has been linked to AAA development and progression. BAK1 abd
✦ LIBER ✦
BAK1 gene variation and abdominal aortic aneurysms
✍ Scribed by Bruce Gottlieb; Lorraine E. Chalifour; Benjamin Mitmaker; Nathan Sheiner; Daniel Obrand; Cherrie Abraham; Melissa Meilleur; Tomoko Sugahara; Ghassan Bkaily; Morris Schweitzer
- Book ID
- 102265714
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 77 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1059-7794
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We thank Ku ¨ry et al. [2010] for their letter. They raise a number of issues with regard to our initial article that reported on variations in BAK1 gene (MIM] 600516) sequence expressed in the abdominal aorta (AA) tissue when compared with leukocyte genomic DNA sequence . In a subsequent letter , w
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