B12-retro-Riboswitches: Guanosyl-Induced Constitutional Switching of B12 Coenzymes
✍ Scribed by Sigrid Gschösser; Bernhard Kräutler
- Book ID
- 102795705
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 714 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0947-6539
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📜 SIMILAR VOLUMES
## Abstract The acid catalyzed heterolytic cleavage of the CoC bond in coenzyme B~12~ (1) was studied using the ‘excess acidity’ functions of Cox and Yates. The results are compared to the acid induced decomposition of (methyl‐5‐deoxy‐ribofuranosyl)‐(2) and (2‐ethoxyethyl)cobalamin (3). Evidence i
## Abstract The acid‐catalyzed heterolytic cleavage of the Co‐C bond in coenzyme B~12~ (1) and adocobinamide hydroxide (2) was studied using the excess‐acidity functions of __Cox__ and __Yates.__ The results are compared to the acid‐induced decomposition of methyl(5′‐deoxyribofuranosyl)cobalamin (3
Pseudocoenzyme B 12 ( Cob-(5'-deoxy-5'-adenosyl)-(adenin-7-yl)cobamide; 1) and adenosyl-factor A ( Cob-(5'-deoxy-5'-adenosyl)-(2-methyladenin-7-yl)cobamide; 3) are two natural analogues of coenzyme B 12 ( adenosylcobalamin-Cob-(5'-deoxy-5'-adenosyl)-(5,6-dimethyl-1H-benzimidazolyl)cobamide; 2), wher