B12-retro-Riboswitches: Constitutional Switching of B12 Coenzymes Induced by Nucleotides
✍ Scribed by Sigrid Gschösser; Karl Gruber; Christoph Kratky; Christian Eichmüller; Bernhard Kräutler
- Book ID
- 101565933
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 222 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0044-8249
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## Abstract The acid catalyzed heterolytic cleavage of the CoC bond in coenzyme B~12~ (1) was studied using the ‘excess acidity’ functions of Cox and Yates. The results are compared to the acid induced decomposition of (methyl‐5‐deoxy‐ribofuranosyl)‐(2) and (2‐ethoxyethyl)cobalamin (3). Evidence i
## Abstract The acid‐catalyzed heterolytic cleavage of the Co‐C bond in coenzyme B~12~ (1) and adocobinamide hydroxide (2) was studied using the excess‐acidity functions of __Cox__ and __Yates.__ The results are compared to the acid‐induced decomposition of methyl(5′‐deoxyribofuranosyl)cobalamin (3