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B cell responses: Regulating receptor editing

โœ Scribed by Bell, Elaine

Book ID
109956172
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
164 KB
Volume
9
Category
Article
ISSN
1474-1741

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B cells that fail to pass a developmental checkpoint, either as immature or mature B cells, can be rescued by creating a new B cell antigen receptor through nested secondary immunoglobulin gene rearrangements, a process termed receptor editing. Tolerance-mediated receptor editing occurs in self-reac