B-cell receptor regulation of peripheral B cells

✍ Scribed by Ian CM MacLennan

• Book ID: 104358971
• Publisher: Elsevier Science
• Year: 1998
• Tongue: English
• Weight: 572 KB
• Volume: 10
• Category: Article
• ISSN: 0952-7915
• DOI: 10.1016/s0952-7915(98)80252-5

✦ Synopsis

Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing cells.