Blood was drawn from 74 children, 3-16 years old, at diagnosis of Type 1 (insulin-dependent) diabetes and before the first insulin injection. Insulin autoantibodies were detected with a polyethylen-glycol-method in 27/74 (36.4%) and with an immuno-electrophoretic method in 6/74 (8.1%). Islet cell cy
✦ LIBER ✦
B-Cell Function and Islet Cell and Other Organ-Specific Autoantibodies in Relatives to Insulin-Dependent Diabetic Patients
✍ Scribed by Nordén, G. ;Jensen, E. ;Stilbo, I. ;Bottazzo, G. F. ;Lernmark, Å.
- Book ID
- 114693259
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Weight
- 397 KB
- Volume
- 213
- Category
- Article
- ISSN
- 0001-6101
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Studying 239 Type 1 (insulin-dependent) diabetic patients and 144 of their first-degree relatives, we found a significant prevalence of autoimmune manifestations in both groups, compared with sex- and age-matched control subjects (p less than 0.001). In particular, in diabetic patients we found a hi