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Islet-cell antibodies and beta-cell function in insulin-dependent diabetics

✍ Scribed by S. Madsbad; G. F. Bottazzo; A. G. Cudworth; B. Dean; O. K. Faber; C. Binder


Publisher
Springer
Year
1980
Tongue
English
Weight
302 KB
Volume
18
Category
Article
ISSN
0012-186X

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Blood was drawn from 74 children, 3-16 years old, at diagnosis of Type 1 (insulin-dependent) diabetes and before the first insulin injection. Insulin autoantibodies were detected with a polyethylen-glycol-method in 27/74 (36.4%) and with an immuno-electrophoretic method in 6/74 (8.1%). Islet cell cy

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The prevalence of islet cell antibodies in children with Type 1 (insulin-dependent) diabetes was determined in a cohort of 678 children. The natural course of islet cell antibodies was followed in 375 children at 1 year, 252 and 135 children after 2 and 3 years respectively. Islet cell antibodies we