A common variable immunodeficiency (CVID) patient, who carries mutations on both alleles of the gene encoding the surrogate light chain component lambda 5/14.1, shows a similar phenotype of B-cell deficiency as the lambda 5-deficient mutant mouse. As discussed here by Paolo Ghia and colleagues, this
B-cell development in man
โ Scribed by Peter D. Burrows; Max D. Cooper
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 884 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0952-7915
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