Azaprostanoids II. Synthesis of 12-azacarboprostacyclin analogs
✍ Scribed by Chia-Lin J. Wang
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 202 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The synthesis of a new carbocyclic nucleoside starting from aucubin, a natural methylcyclopentanoid monoterpene, has been performed, allowing the preparation of aucubovir II, a carbocyclic nucleoside analog with a highly functionalized
The title compound is synthesized from the corresponding 2',3'-O-isopropylidene nucleoside with POCl in trimethylphosphate. The anomers are separated by preparative HPLC.
## Abstract The indole (1) and chroman analogs (2) of mevinolin and their 6__S__ diastereomers 15c and 25d were synthesized in several steps starting with methyl (__R__)‐3‐[(tert‐butyldimethylsilyl)oxy]‐4‐formylbutyrate (12) and 2‐(indol‐3‐yl)ethanol (3) or 6‐methoxychroman‐4‐one (16), respectively