Azapeptides as Inhibitors and Active Site Titrants for Cysteine Proteinases
β Scribed by Xing, Ruye; Hanzlik, Robert P.
- Book ID
- 126399022
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 118 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0022-2623
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Peptidyl methylcoumarin amides are well established as model substrates for understanding protease specificity, but the corresponding methylcoumarin esters have attracted scant attention despite their potential utility in active-site titration and mechanistic characterization. We have devised techni