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Axin1 and Axin2 Are Regulated by TGF-β and Mediate Cross-talk between TGF-β and Wnt Signaling Pathways

✍ Scribed by DEBBIE Y. DAO; XUE YANG; DI CHEN; MICHAEL ZUSCIK; REGIS J. O'KEEFE

Book ID
111483603
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
232 KB
Volume
1116
Category
Article
ISSN
0890-6564

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Signaling through both the transforming growth factor b (TGFb) superfamily of growth factors and Notch play crucial roles during embryonic pattern formation and cell fate determination. Although both pathways are able to exert similar biological responses in certain cell types, a functional interact