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Avoidance of Colostomy Placement in Advanced Colorectal Cancer with Twice Weekly Hypofractionated Radiation Plus Continuous Infusion 5-Fluorouracil

✍ Scribed by Nora A Janjan; Tara Breslin; Renato Lenzi; Tyvin A Rich; John Skibber


Book ID
114266167
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
114 KB
Volume
20
Category
Article
ISSN
0885-3924

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Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer