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Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2

✍ Scribed by Gresko, Ekaterina; Roscic, Ana; Ritterhoff, Stefanie; Vichalkovski, Anton; del Sal, Giannino; Schmitz, M Lienhard


Book ID
110031464
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
308 KB
Volume
25
Category
Article
ISSN
0261-4189

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## Abstract The E6 and E7 proteins of human papillomaviruses (HPV) play a crucial role in the pathogenesis of malignant tumors. E6 protein of high‐risk mucosal papillomaviruses targets a number of proteins for proteosomal degradation through complex formation with ubiquitin ligase E6AP. These prote