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Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3

✍ Scribed by Terry J. Miller; Randal J. Schneider; James A. Miller; Brad P. Martin; Muayyad R. Al-Ubaidi; Neeraj Agarwal; Lloyd A. Dethloff; Martin A. Philbert


Book ID
116779617
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
809 KB
Volume
27
Category
Article
ISSN
0161-813X

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## Abstract Multiple myeloma (MM) is a malignancy characterized by the accumulation of tumoral plasma cells in bone marrow. This disease remains incurable and the development of new therapeutic strategies is urgently required. We have studied the effects of 2 selective estrogen receptor disrupters