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Automated synthesis of [11C]-(+)-PHNO from [11C]methyl iodide

✍ Scribed by S. Francisco Garcia-Arguello; Erik Arstad; Diane Brickute; Sajinder K. Luthra; David R. Turton; Matthias Glaser; Robin Fortt; Edward G. Robins

Book ID
119331430
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
62 KB
Volume
52
Category
Article
ISSN
1053-8119

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On-line [11C]methylation using [11C]meth
On-line [11C]methylation using [11C]methyl iodide for the automated preparation of 11C-radiopharmaceuticals
✍ Ren Iwata; Claudio Pascali; Mitsuaki Yuasa; Kazuhiko Yanai; Toshihiro Takahashi; πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science βš– 578 KB

A novel method for the efficient preparation of 11C-radiopharmaceuticals by on-line [11C]methylation using [11C]methyl iodide has been developed and applied to a rapid, convenient automated system. [11C]Methyl iodide is first trapped in a short column, containing an adsorber and coated substrate, wh