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Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2′-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry

✍ Scribed by Trine Henriksen; Peter R. Hillestrøm; Henrik E. Poulsen; Allan Weimann


Book ID
113630908
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
517 KB
Volume
47
Category
Article
ISSN
0891-5849

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## Abstract A rapid and high‐throughput method for the determination of urinary levels of the oxidative stress biomarker, 8‐hydroxy‐2′‐deoxyguanosine (8‐OH‐dG), has been developed and validated using liquid chromatography combined with electrospray ionization tandem mass spectrometry (LC‐MS/MS). Th