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Automated analysis of antiepileptic drugs in serum by column-switching high-performance liquid chromatography

✍ Scribed by Albert Nazareth; Luis Jaramillo; Barry I. Karger; Roger W. Giese; Lloyd R. Snyder


Book ID
107996439
Publisher
Elsevier Science
Year
1984
Weight
753 KB
Volume
309
Category
Article
ISSN
0378-4347

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp