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Autocrine release of TGF-β by portal fibroblasts regulates cell growth

✍ Scribed by Rebecca G Wells; Emma Kruglov; Jonathan A Dranoff

Book ID: 117106230
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 167 KB
Volume: 559
Category: Article
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(04)00037-7

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Transforming growth factor-beta (TGF-P) is a polypeptide with multiple physiological functions. lsoforms of this growth factor have important roles in control of the cell cycle, in regulation of cell-cell interactions and in growth and development. Malignant transformation has been shown to be assoc