Autoantibodies to thymus and skin epithelium in NZB/N mice and (NZB × NZW)F1hybrids
✍ Scribed by I. M. Lyampert; E. V. Ryzhikova; G. N. Pleskovskaya; V. A. Nasonova
- Book ID
- 104969119
- Publisher
- Springer US
- Year
- 1986
- Tongue
- English
- Weight
- 803 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0007-4888
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## Proliferation of Ly-1 B cells in autoimmune NZB and (NZB X NZW)F1 mice* Spontaneous autoimmune disease in NZB and (NZB x NZW)FI (B/W) mice is associated with a spectrum of lymphoproliferative abnormalities, but the relationship between autoimmunity and lymphoproliferation is poorly understood.
## Abstract Anti‐nuclear antibodies could be demonstrated in sero‐negative patients with immune complex glomerulonephritis by means of an acid dissociation method. The antibodies were also found in sero‐negative NZB and (NZB × NZW) F~1~ mice with complex glomerulonephritis. It is suggested that t