Acute promyelocytic leukemia (APL) is a subset of acute myeloid leukemia characterized by the morphology of the blast cells (M3 type in the FAB nomenclature), and a specific t(15;17) translocation. APL was further characterized by a specific sensitivity to all-trans retinoic acid's differentiation e
Auer rods and differentiation in acute promyelocytic leukemia
β Scribed by Fabien Zassadowski; Lionel Ades; Marie-Helene Schlageter; Sylvie Chevret; Isabelle Guillemot; Pierre Fenaux; Christine Chomienne; Bruno Cassinat
- Book ID
- 108675893
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 100 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0007-1048
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One hundred and twenty-five cases of acute myeloid leukemia (AML) were reviewed for the presence of Auer rods by two peroxidase methods. The percentage of Auer rods recognized by Wright-Giemsa (WG) staining was 20.8% but three times higher by peroxidase staining techniques using either benzidine bas
## Abstract Sixteen children (ages 2β17) with acute promyelocytic leukemia (APL) were studied retrospectively. Diagnosis was based on clinical features and morphological criteria of the FAB classification. Bleeding diathesis was the predominant presenting symptom (>85%), associated with laboratory