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Attenuation of conflict-induced suppression by clonidine: Indication of anxiolytic activity

✍ Scribed by Hansjoerg Kruse; Robert W. Dunn; Karin L. Theurer; William J. Novick; Gary T. Shearman


Book ID
102146419
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
409 KB
Volume
1
Category
Article
ISSN
0272-4391

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The effects of clonidine on avoidance acquisition and locomotor activity were studied in male Wistar rats with 5,6-dihydroxytryptamine (5,6-DHT) lesions of the median raphe nucleus. Lesioned animals showed marked depletion in forebrain serotonin and 5-hydroxyindole acetic acid concentrations. Clonid