Suppression of actively induced experimental autoimmune uveoretinitis by CD4+T cells
✍ Scribed by Eiichi Uchio; Masaya Kijima; Misaki Ishioka; Shun-ichi Tanaka; Shigeaki Ohno
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 645 KB
- Volume
- 235
- Category
- Article
- ISSN
- 0065-6100
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A key question in the field of autoimmunity concerns the fact that experimental disease is generally induced more easily with closely related, but not completely identical, tissue‐restricted antigens. Here, the possibility that naturally occurring regulatory T cells (Tregs) for self‐ant
## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a
## Depletion of CD8+ Tcells suppresses the development of experimental autoimmune myasthenia gravis in Lewis rats To understand the role of CD8+ T cells in experimental autoimmune myasthenia gravis (EAMG), CD8+ Tcells were depleted by injecting a monoclonal anti-rat CD8 antibody (0x8) into Lewis r