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CD4+CD25+T regulatory cells induced by LPS-activated bone marrow dendritic cells suppress experimental autoimmune uveoretinitis in vivo

✍ Scribed by Kirsten Siepmann; Sabine Biester; Jarmila Plšková; Elizabeth Muckersie; Linda Duncan; John V. Forrester


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
333 KB
Volume
245
Category
Article
ISSN
0065-6100

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a