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Attenuated adenomatous polyposis coli

โœ Scribed by Marina H. Wallace; Ian M. Frayling; Susan K. Clark; Kay Neale; Robin K. S. Phillips


Publisher
Springer
Year
1999
Tongue
English
Weight
623 KB
Volume
42
Category
Article
ISSN
0012-3706

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Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gene p