Attenuated Familial Adenomatous Polyposis
โ Scribed by JamesM. Church; GeraldS. Hernegger; HarveyG. Moore; JoseG. Guillem
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 239 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0012-3706
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Familial adenomatous polyposis (FAP) is an inherited colon cancer syndrome caused by mutations in the APC gene on chromosome region 5q21. Patients typically present with several hundred to several thousand polyps throughout the colon. Benign and malignant extracolonic manifestations are often presen
A family is presented with attenuated familial adenomatous polyposis of variable phenotype. The clinical features range from sparse right-sided polyposis and cancer in the proximal colon at the age of 34 to pan-colonic polyposis and cancer at the age of 68. Rectal sparing is common to all affected m