𝔖 Bobbio Scriptorium
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Attempted hybridizations with senescent human fibroblasts

✍ Scribed by John W. Littlefield

Publisher
John Wiley and Sons
Year
1973
Tongue
English
Weight
262 KB
Volume
82
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

If the aging of diploid human fibroblasts reflects stable genetic or epigenetic changes which are few in number and different in different cells, then complementation could occur in hybrids between individual senescent cells. However neither pairs of aged fibroblasts nor even pairs of young and senescent fibroblasts produce viable hybrids under conditions known to promote cell fusion.

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