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ATP-dependent chromatin remodeling factors and DNA damage repair

✍ Scribed by Mary Ann Osley; Toyoko Tsukuda; Jac A. Nickoloff

Book ID: 113808916
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 220 KB
Volume: 618
Category: Article
ISSN: 0027-5107
DOI: 10.1016/j.mrfmmm.2006.07.011

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The eukaryotic genome is packaged into a periodic nucleoprotein structure termed chromatin. The repeating unit of chromatin, the nucleosome, consists of DNA that is wound nearly two times around an octamer of histone proteins. To facilitate DNA-directed processes in chromatin, it is often necessary