## Abstract The thermodynamics of the DNA helix‐coil transition is studied, starting from the thermodynamical potential difference between the states helix and coil; this potential difference is understood as the difference in free energies. With only three parameters obtained from experimental dat
Atomistic Simulation of the DNA Helix−Coil Transition †
✍ Scribed by Piana, Stefano
- Book ID
- 127032234
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 272 KB
- Volume
- 111
- Category
- Article
- ISSN
- 1089-5639
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📜 SIMILAR VOLUMES
## Abstract The broadening of a helix–coil transition due to base pair heterogeneity is calculated on the basis of a cumulant perturbation expansion in the quasi‐grand ensemble. In this ensemble the fictitious, homogeneous chain, to which the perturbation is referred, automatically decreases its co
A simplified model for the closed circular DNA (ccDNA) is proposed to describe some specific features of the helix-coil transition in such molecules. The Hamiltonian of ccDNA is related to the one introduced earlier for the open chain DNA (ocDNA). The basic assumption is that the reduced energy of t
## Abstract The helix–coil phase transition of DNA is studied through a model equivalent to the one used in the theory of superconductivity. A distribution function for the excitations analogous to the usual Fermi function is obtained which depends on the parameter __T__~__0__~, the maximum tempera
## Abstract We show that the fine oscillatory structure of the DNA melting curve can be used to determine explicitly the nucleotide composition and the order of certain domains within the DNA. If DNA is specifically fragmented, the order of fragments can be learned directly from a comparison of the
## Values of the rue a~ which an alkrnaring copolymcric nucleic acid mclw ar~er a hzmpcn~urejump have been oblaincd wilh a Monle Carlo simulation. Using a Glauber-king scheme 10 model the dynamics. the helix-random coil transilion shows a pure "monodispersive" rslaxalion in accord with previous an