## Abstract The helix–coil transition of DNA of various base compositions has been followed by measuring the heat capacity and the ultraviolet absorption as a function of temperature through the transition region. The results of these measurements indicate that the transition enthalphy Δ__H__ for a
Thermodynamics of the DNA helix-coil transition
✍ Scribed by Jordi Porta
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 311 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0020-7608
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The thermodynamics of the DNA helix‐coil transition is studied, starting from the thermodynamical potential difference between the states helix and coil; this potential difference is understood as the difference in free energies. With only three parameters obtained from experimental data different quantities of the T~2~ phage DNA molecule are calculated. It is observed that the phase transition is of second order.
📜 SIMILAR VOLUMES
## Abstract The broadening of a helix–coil transition due to base pair heterogeneity is calculated on the basis of a cumulant perturbation expansion in the quasi‐grand ensemble. In this ensemble the fictitious, homogeneous chain, to which the perturbation is referred, automatically decreases its co
A simplified model for the closed circular DNA (ccDNA) is proposed to describe some specific features of the helix-coil transition in such molecules. The Hamiltonian of ccDNA is related to the one introduced earlier for the open chain DNA (ocDNA). The basic assumption is that the reduced energy of t
## Abstract The helix–coil phase transition of DNA is studied through a model equivalent to the one used in the theory of superconductivity. A distribution function for the excitations analogous to the usual Fermi function is obtained which depends on the parameter __T__~__0__~, the maximum tempera
## Abstract We show that the fine oscillatory structure of the DNA melting curve can be used to determine explicitly the nucleotide composition and the order of certain domains within the DNA. If DNA is specifically fragmented, the order of fragments can be learned directly from a comparison of the
## Abstract The effect of magnesium ions on the parameters of the DNA helix‐coil transition has been studied for the concentration range 10^−6^–10^−1^__M__ at the ionic strengths of 10^−3^__M__ Na^+^. Special attention has been given to the region of low ion concentrations and to the effect of poly