## Abstract Hybrid clones were obtained between a mouse cell line (3TP) and a temperatureβsensitive Chinese hamster cell line (K12) unable to grow at 40Β° because of a __ts__ defect apparently located at the G1/S transition. The great majority of hybrid clones grew at 40Β°, showing the __ts__ defect
β¦ LIBER β¦
Asynchronous DNA replication and asymmetrical chromosome loss in Chinese hamster-mouse somatic cell hybrids
β Scribed by T. Labella; G. Colletta; G. Marin
- Book ID
- 112558925
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 444 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1572-9931
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## Abstract Somatic hybrids obtained by the selective method of Littlefield between a permanent line of Chinese hamster cells (Wg3) and one of mouse cells (3TP) showed a preponderance of biarmed (hamster) chromosomes. Under normal culture conditions (37Β°) the doubling time of the parental mouse cel