Propagation of two species of mitochondrial DNA in Chinese hamster-mouse somatic cell hybrids
β Scribed by Laura DeFrancesco
- Book ID
- 112559451
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 810 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1572-9931
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Hybrid clones were obtained between a mouse cell line (3TP) and a temperatureβsensitive Chinese hamster cell line (K12) unable to grow at 40Β° because of a __ts__ defect apparently located at the G1/S transition. The great majority of hybrid clones grew at 40Β°, showing the __ts__ defect
The maintenance of mtDNA has been examined in human intraspecific hybrid cells constructed from the fusion of HEB7A, a HeLa tumor cell line carrying the mitochondrially coded chloramphenical (CAP) resistance mutation, and GM 2291, a limited lifespan human diploid fibroblast which is CAP sensitive. T