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Asymmetric synthesis of ω-bromo-2(S)-azido acids as precursors for the synthesis of novel amino acids

✍ Scribed by Joseph T. Lundquist IV; Thomas A. Dix

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
208 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

A series of o3-bmmo-2(S)-azido acids with side-chain lengths ranging from 3-5 methylene units has been synthesized. These intermediates enable the facile synthesis of chiral non-natural amino acids containing virtually any nucleophile capable of substituting the o3-bromo group.

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