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Asymmetric Synthesis of α-Amino-γ-nitrocarboxylic Esters by the Bislactim Ether Method

✍ Scribed by Prof. Dr. Ulrich Schöllkopf; Dipl.-Chem. Wulf Kühnle; Dr. Ernst Egert; Michael Dyrbusch


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
320 KB
Volume
26
Category
Article
ISSN
0044-8249

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g-Hydroxy-a,b-acetylenic esters containing three adjacent and structurally very different functional groups are very useful in the synthesis of highly functionalized organic molecules. [1, 2] This class of compound is normally prepared by treatment of an alkyl propiolate with nBuLi at À78 8C