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Asymmetric synthesis of the diastereoisomers of the leukotriene B4 antagonist, U-75302

โœ Scribed by Carmen E. Burgos; Eldon G. Nidy; Roy A. Johnson

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
245 KB
Volume
30
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A synthesis of the four diastereoiromers of U-75302 has been completed using (@ and (g)glycidol as the precursors to theC5 chiral centers and asymmetric reductions of a ketone to generate the Cl2 centers.

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