The asymmetric synthesis of methyl (S)-6,8-dihydroxyoctanoate ( ) and (S)-6,8-dimethylsulfonyloxyoctane-1-carboxylic acid (13), key precursors to R-(+)-a-lipoic acid (6) is described using OsO 4 -catalyzed asymmetric dihydroxylation and Ru-catalyzed asymmetric hydrogenation, respectively, as the key
β¦ LIBER β¦
Asymmetric synthesis of (R)-reticuline. A new strategy for the asymmetric synthesis of isoquinolines via enantioselective epoxidation or dihydroxylation
β Scribed by Rolf Hirsenkorn
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 300 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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