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Asymmetric Synthesis of Quaternary Centers. Total Synthesis of (−)-Malyngolide

✍ Scribed by Trost, Barry M.; Tang, Weiping; Schulte, Jörg L.


Book ID
126775722
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
49 KB
Volume
2
Category
Article
ISSN
1523-7060

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📜 SIMILAR VOLUMES


Asymmetric hetero Diels–Alder route to q
✍ Arun K Ghosh; Michio Shirai 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 103 KB

Conformationally constrained chiral bis(oxazoline)-metal complex catalyzed asymmetric hetero Diels-Alder reactions of Danishefsky's diene and a variety of α-keto esters constructed quaternary carbon centers enantioselectively. The reaction was utilized in the synthesis of (-)-malyngolide.

ChemInform Abstract: Asymmetric hetero D
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d- and l-Erythrose as sources of chiral
✍ Alexandros E. Koumbis; Kyriaki M. Dieti; Myrofora G. Vikentiou; John K. Gallos 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 194 KB

A highly efficient and versatile approach was applied for the total synthesis of the marine natural products (-)-malyngolide and (+)-tanikolide from isopropylidene L-and D-erythrose, using a common strategy.