𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric synthesis of protected α-alkyl-β-amino-δ-hydroxy esters by stereocontrolled elaboration of THYM*

✍ Scribed by Giuseppe Guanti; Alberto Moro; Enrica Narisano


Book ID
108379704
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
155 KB
Volume
41
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A facile and stereocontrolled synthesis
✍ Alessandra Maria Nocioni; Carmela Papa; Claudia Tomasini 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 215 KB

The diastereoselective synthesis of syn-a-alkyl a-hydroxy 13-amino acids 4a-h was easily accomplished by reaction of the sodium dianion of the corresponding anti a-alky113-benzoylamino acid methyl esters with iodine. The intermediate a-iodo derivatives spontaneously afforded c/s-oxazolines which, up