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ChemInform Abstract: Asymmetric Synthesis of Protected α-Alkyl-β-amino-δ-hydroxy Esters by Stereocontrolled Elaboration of THYM*.

✍ Scribed by Giuseppe Guanti; Alberto Moro; Enrica Narisano


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Aziridine 2-Carboxy
✍ F. A. DAVIS; G. V. REDDY; C.-H. LIANG 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

Aziridine 2-Carboxylate Ester Mediated Asymmetric Synthesis of α-Alkyl β-Amino Acids. -Highly stereoselective reductive ring opening of the N-tosylaziridines (II) with LiAlH4 followed by oxidation of the syn-amino alcohols (III) provides an efficient entry to the asymmetric synthesis of αmethyl β-am