Synthesis of β-Amino-α-hydroxy Esters and β-Amino-α-azido Ester by Sharpless Asymmetric Aminohydroxylation, Byproducts Analysis
✍ Scribed by Liu, Zuosheng; Ma, Nianchun; Jia, Yanxing; Bois-Choussy, Michèle; Malabarba, Adriano; Zhu, Jieping
- Book ID
- 126937360
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 116 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0022-3263
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract 3‐Aryl‐3‐azido‐2‐hydroxypropanoic esters, prepared from the corresponding 3‐aryl‐oxirane‐2‐carboxylic esters by ring opening with sodium azide, were reduced with tin(II) chloride dihydrate in methanol to give 3‐amino‐3‐aryl‐2‐hydroxypropanoic esters in good yields. Under these condition
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