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Asymmetric synthesis of malic acid-type synthons VIA chiral norephedrine-derived oxazolidines

โœ Scribed by Anna Bernardi; Silvia Cardani; Carlo Scolastico; Roberto Villa


Book ID
108372302
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
820 KB
Volume
46
Category
Article
ISSN
0040-4020

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Asymmetric synthesis of chiral synthons
โœ Keisuke Suzuki; Takeshi Ohkuma; Mayumi Miyazawa; Gen-ichi Tsuchihashi ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 220 KB

A method is described for the synthesis of chiral alkynyl ketones and alkynols via trimethylaluminum-promoted pinacol-type rearrangement where alkynyl groups behave as "the staying group", followed by stereoselective reduction leading to the latter.