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Asymmetric synthesis of chiral 4-substituted 5,5-diethyl oxazolidin-2-ones as potential effective chiral auxiliaries

✍ Scribed by Li, J.-F. ;Yang, R. ;Nie, L. ;Huang, R. ;Lin, J.


Book ID
110893930
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
98 KB
Volume
66
Category
Article
ISSN
1397-002X

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A study of 4-substituted 5,5-diaryl oxaz
✍ Colin L. Gibson; Karen Gillon; Stuart Cook πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 251 KB

A series of three 5,5-diaryl substituted oxazolidin-2-ones (diphenyl, dinaphthyl and ditolyl) have been prepared and shown to be particularly effective chiral auxiliaries to afford high yields and diastereoselectivities for alkylation and azidations of their N-acyl derivatives. The 5,5-ditolyl oxazo