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4-Substituted-5,5-dimethyl oxazolidin-2-ones as effective chiral auxiliaries for enolate alkylations and Michael additions

✍ Scribed by Stephen G. Davies; Hitesh J. Sanganee


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
202 KB
Volume
6
Category
Article
ISSN
0957-4166

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A study of 4-substituted 5,5-diaryl oxaz
✍ Colin L. Gibson; Karen Gillon; Stuart Cook πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 251 KB

A series of three 5,5-diaryl substituted oxazolidin-2-ones (diphenyl, dinaphthyl and ditolyl) have been prepared and shown to be particularly effective chiral auxiliaries to afford high yields and diastereoselectivities for alkylation and azidations of their N-acyl derivatives. The 5,5-ditolyl oxazo